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Updated: May 8, 2026

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
Published on: July 27, 2022
[Biocomposite nanostructured materials for the bone defects filling by osteomyelitis]
Abstract:
Results of the use of the biocomposite nanostructured material "KollapAn" in the treatment of 374 patients with osteomyelitis were followed up. 412 operations were performed, depending on the stage of the inflammatory process and clinical picture. Majorly, operation was performed on the 5-7th day after primary necrosequestrectomy. Good early anatomic results were achieved in 86% patients. All patients demonstrated the good functional results of the treatment; the wound healing was on-time. The lethality rate was 1.2%; all these patients had severe sepsis. The long-term follow up (1.5 years) revealed the complete substitution of the bone defect by the autobone; no cases of the osteomyelitis recurrence were observed.
