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A general strategy for dual-triggered combined tumor therapy based on template semi-graphitized mesoporous silica
Yi Wang1, Kaiyuan Wang, Xueying Yan
1Center of Analysis and Measurement, Fudan University, Shanghai, 200433, China.
Abstract:
A general strategy is developed for dual-triggered chemo-photothermal tumor therapy based on template semi-graphitized mesoporous silica nanoparticles (TsGMSN). The strategy endues classic MSN with new charming properties, while easily escaping from toxicity of the surfactant. The doxorubicin-loaded system (TsGMSND) exhibits synergistic heat-stimulative, pH-responsive, and sustained release, and effective combined tumor therapy.
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