Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Physiological Control of Respiration01:23

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Hyperpnea and Hyperventilation01:25

Hyperpnea and Hyperventilation

Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...
Chronic Obstructive Pulmonary Disease-V: Nursing Management01:30

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding the perceptions and experiences of adults with early-onset neuromuscular disorders using noninvasive ventilation in making healthcare decisions.

ERJ open research·2026
Same author

Assessing new treatments for central sleep Apnoea in heart failure: sample size considerations for reliable detection of safety signals.

Sleep & breathing = Schlaf & Atmung·2025
Same author

Advance care planning in patients with respiratory failure.

European respiratory review : an official journal of the European Respiratory Society·2024
Same author

Home mechanical ventilation in slowly progressive neuromuscular disease: challenging perceptions of health-related quality of life.

Thorax·2023
Same author

Effect of adaptive servo ventilation on central sleep apnea and sleep structure in systolic heart failure patients: polysomnography data from the SERVE-HF major sub study.

Journal of sleep research·2022
Same author

Update June 2022: management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline.

The European respiratory journal·2022

Related Experiment Video

Updated: May 8, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
07:15

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

Chronic hypoventilation and its management.

Anita K Simonds1

  • 1Royal Brompton and Harefield NHS Foundation Trust, London, UK. A.Simonds@rbht.nhs.uk

European Respiratory Review : an Official Journal of the European Respiratory Society
|September 3, 2013
PubMed
Summary

Nocturnal hypoventilation is common in chronic ventilatory disorders, preceding daytime failure. This review compares management of hypoventilation in neuromuscular disease versus obesity hypoventilation syndrome.

Area of Science:

  • Pulmonary Medicine
  • Sleep Medicine
  • Critical Care

Background:

  • Nocturnal hypoventilation is highly prevalent in chronic ventilatory disorders, often preceding daytime respiratory failure.
  • Obstructive sleep apnoea syndrome receives more attention, but hypoventilation syndromes are significant clinical concerns.
  • Understanding the spectrum of hypoventilation is crucial for effective patient management.

Purpose of the Study:

  • To review the clinical management of chronic hypoventilation in neuromuscular disease.
  • To compare this management with that of obesity hypoventilation syndrome.
  • To elucidate the differing pathophysiological mechanisms underlying these conditions.

Main Methods:

  • Literature review focusing on clinical management strategies.

Related Experiment Videos

Last Updated: May 8, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
07:15

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

  • Comparative analysis of hypoventilation in neuromuscular disease and obesity hypoventilation syndrome.
  • Discussion of underlying respiratory physiology and load-intolerance.
  • Main Results:

    • Neuromuscular disease causes hypoventilation due to reduced respiratory system capacity.
    • Obesity hypoventilation syndrome results from increased ventilatory load intolerance.
    • Distinct management approaches are required for these differing etiologies.

    Conclusions:

    • Chronic hypoventilation management requires tailored strategies based on underlying cause.
    • Neuromuscular disease and obesity hypoventilation syndrome represent opposite ends of the respiratory load spectrum.
    • Further research into optimizing management for these prevalent conditions is warranted.