Anatomy of Main Coronary Artery Location: Radial Position around the Aortic Root Circumference
Zakaria Almuwaqqat1, Maryann Tranquilli, John Elefteriades
1Section of Cardiac Surgery, Yale University School of Medicine, New Haven, Connecticut.
Insights
The average angular separation between the right and left coronary ostia in humans is 122.9 degrees. This key coronary artery anatomy differs significantly from porcine aortic roots used in aortic root replacement surgery.
Area of Science:
- Cardiovascular Anatomy
- Surgical Anatomy
- Medical Imaging
Background:
- Accurate radial positioning of coronary ostia is crucial for composite graft operations during aortic root replacement.
- Existing knowledge gaps regarding coronary ostial angulation can lead to critical intraoperative orientation errors and patient ischemia.
Purpose of the Study:
- To precisely quantify the radial and angular relationship of the native right and left coronary ostia in humans.
- To compare human coronary ostial anatomy with that of commonly used porcine aortic roots in aortic root replacement.
Main Methods:
- High-definition computed tomography (CT) scans were utilized to assess coronary ostial location in 100 patients (75 aneurysm, 25 control).
- Geometric calculations determined the angular separation between the center points of the right and left coronary ostia relative to the aortic lumen center.
Main Results:
- The mean angular separation between the right and left coronary ostia was 122.9 degrees, with low individual variation (SD 13.1 degrees).
- This angle was consistent across aneurysm and control groups, and between bicuspid and tri-leaflet aortic valves.
- A significant difference was observed compared to the 145-degree angulation typically found in porcine aortic roots.
Conclusions:
- The normal human angular separation of coronary ostia is approximately 122.9 degrees, a critical anatomical landmark for aortic root surgery.
- This human anatomy differs substantially from porcine aortic roots, necessitating intraoperative awareness and informing the design of novel composite grafts.
Abstract:
There is a relative dearth of fundamental anatomic information regarding the radial component of right and left coronary ostial location along the circumference of the aortic root. Recent literature has emphasized the importance of this anatomic component in the orientation of coronary buttons for the composite graft operation, especially as regards the use of porcine biological roots or design of novel mechanical or biological composite grafts. Problems in orientation of reattached buttons can lead to life-threatening ischemia. We assessed the radial location of native coronary arteries or coronary artery buttons by high-definition computed tomography scan in 100 patients (75 consecutive aneurysm patients undergoing aortic root replacement [ARR] and 25 control patients undergoing coronary artery bypass). We excluded six patients with unclear coronary anatomy and one with an anomalous origin. The center point of the aortic lumen was located, radii were drawn from there to each coronary ostium, and the angle was computed geometrically. The mean angle between the radii for the right and left coronary ostia was 122.9 degrees. The angle was similar for bicuspid and tri-leaflet aneurysm patients, 121.0 and 122.7 degrees, respectively. The angle was similar for aneurysm patients (121.6 degrees) and for controls (126.5 degrees). The angle showed very little variation among individuals for the overall group (standard deviation [SD] 13.1 degrees), for the aneurysm patients (SD 13.4 degrees), and for the controls (SD 12 degrees). This angle is different from that of the porcine roots (145 degrees) which are commonly used for ARR. The normal human angular separation between the right and left coronary ostia is 122.9 degrees for both aneurysm and control patients. This anatomic relationship is very different from that of porcine aortic roots. This anatomy needs to be borne in mind intraoperatively. This anatomic relationship can be used in the design of novel aortic root biological or composite grafts.
Related Concept Videos
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
The Aorta
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
Location and Orientation of the Heart
Arteries of the Upper Limbs
Thoracic Aorta


