Related Experiment Video
Updated: May 8, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Cardiac device infection due to Streptococcus pneumoniae
Theresa T Liu1, Pablo B Nery, David Birnie
1Division of Infectious Diseases, University of Ottawa/The Ottawa Hospital;
Abstract:
Cardiac device infections (CDIs) are recognized complications of device implantation. Most CDIs are caused by skin flora but can also result from hematogenous seeding of the device. A case involving Streptococcus pneumoniae CDI, which is rare, potentially vaccine preventable and may not be associated with overt antecedent pneumococcal infection, is reported.
Insights
Cardiac device infections (CDIs) are usually from skin bacteria. This case highlights a rare Streptococcus pneumoniae CDI, which may be preventable with vaccines and can occur without obvious prior infection.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Cardiac device infections (CDIs) are known complications following implantation.
- Most CDIs originate from skin flora, but hematogenous spread is also a cause.
- Streptococcus pneumoniae is an uncommon pathogen in CDIs.
Observation:
- A rare case of CDI caused by Streptococcus pneumoniae was identified.
- The patient did not present with overt signs of pneumococcal infection.
- This presentation is atypical for Streptococcus pneumoniae infections.
Findings:
- Streptococcus pneumoniae can cause cardiac device infections.
- CDIs by this pathogen may not be preceded by typical pneumococcal symptoms.
- This specific CDI is potentially vaccine-preventable.
Implications:
- Highlights the need to consider Streptococcus pneumoniae in CDI etiology, even without typical preceding symptoms.
- Suggests potential for vaccine-preventable strategies in managing CDIs.
- Broadens the understanding of pathogens involved in cardiac device infections.
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