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Recurrent fevers and failure to thrive in an infant
David R Scott1, Sarah Chan, Johanna Chang
1Scripps Clinic, Department of Medicine, San Diego, CA 92130, USA. deardrscott@gmail.com
Allergy and Asthma Proceedings
|September 4, 2013
Summary
This case study details a young boy with recurrent fevers, arthritis, and diarrhea, highlighting a rare immunodeficiency. Early diagnosis and treatment are crucial for managing complex pediatric inflammatory conditions.
Area of Science:
- Pediatric immunology
- Clinical genetics
- Infectious diseases
Background:
- Recurrent fevers, arthritis, and failure to thrive in infants can indicate underlying immune system dysfunction.
- Consanguinity and geographic origin (India) may suggest specific genetic predispositions.
Observation:
- A 2-year-old boy presented with oral ulcers, lymphadenopathy, chronic diarrhea, developmental delay, and polyarticular arthritis.
- Herpes simplex virus 1 viremia and osteopenia with joint erosions were identified.
Findings:
- The patient exhibited symptoms suggestive of a primary immunodeficiency disorder.
- Comprehensive immunologic and genetic evaluations were performed to identify the specific condition.
Implications:
- This case underscores the importance of a thorough diagnostic approach for infants with complex, recurrent symptoms.
- Understanding the immunologic and genetic basis is key for effective therapeutic strategies in pediatric inflammatory diseases.
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01:25Increased Body Temperature
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01:25Types of Fever
Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
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01:22Methods of reducing fever
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Pharmacological Methods of Reducing Fever:
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01:22Development of Immunocompetence
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