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Platelet 5-HT uptake in post-stroke depression

S Barry1, O M Phillips, D C Williams

  • 1Department of Psychiatry, Trinity College Medical School, St. James's Hospital, Dublin, Ireland.

Acta Psychiatrica Scandinavica
|July 1, 1990
PubMed

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G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.