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Related Experiment Video

Updated: May 8, 2026

FIBS-enabled Noninvasive Metabolic Profiling

FIBS-enabled Noninvasive Metabolic Profiling

Published on: February 3, 2014

Company profile: Sistemic Ltd.

¹West of Scotland Science Park, Block 3, Unit 3-5, Kelvin Campus, Glasgow G20 0SP, UK. jim.reid@sistemic.co.uk

Regenerative Medicine

|September 4, 2013

Summary

Sistemic Ltd uses its proprietary SistemQC™ technology and microRNA (miRNA) analysis to ensure the safety and efficacy of cell and gene therapy (CT) products. This approach aids in product characterization, optimization, and potency assessment for improved human health outcomes.

Area of Science:

Biotechnology
Regenerative Medicine
Molecular Biology

Background:

Cell and gene therapy (CT) products offer transformative potential for treating major diseases like diabetes, dementia, and cardiovascular conditions.
Ensuring the safety, efficacy, and cost-effectiveness of these advanced therapies is critical for widespread healthcare adoption.
Sistemic Ltd, founded in 2009, is a global company focused on advancing the CT industry.

Purpose of the Study:

To introduce and explain the application of Sistemic's proprietary SistemQC™ technology for CT product development.
To highlight the role of microRNAs (miRNAs) as biomarkers for understanding cell identity and function in CT products.
To demonstrate how miRNA profiling enhances the characterization, process optimization, and potency assessment of CT products.

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Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia

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Main Methods:

Utilizing IP-protected SistemQC™ technology for in-depth analysis of CT products.
Employing the diagnostic power of microRNAs (miRNAs), a class of ncRNAs regulating gene expression.
Interpreting cell- and tissue-specific miRNA expression profiles to understand cell populations.

Main Results:

SistemQC™ technology provides enhanced understanding of CT product characterization, process optimization, and potency.
miRNA profiles reveal cell identity and functional capabilities, offering insights into phenotypic differences.
This knowledge enables CT companies to comprehensively assess and improve their cell products.

Conclusions:

Sistemic's approach, leveraging SistemQC™ and miRNA analysis, is crucial for ensuring the safety and efficacy of cell and gene therapies.
The technology facilitates cost-effective production, making transformative treatments more accessible.
By providing deeper insights into cell populations, Sistemic empowers the development of next-generation medicines.