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Updated: May 8, 2026

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
[Corneal transplant in a second level hospital. A survival analysis]
Sergio E Hernández-Da Mota1, Margarita Paniagua Jacobo, Gustavo Gómez Revuelta
1Hospital General Dr. Miguel Silva, Morelia, Mich, México. tolodamota@yahoo.com.mx.
Objective:
To determine the long-term corneal graft survival in patients of General Hospital Dr. Miguel Silva.
Materials And Methods:
This was a retrospective cohort study. Records from patients who underwent corneal transplant surgery at General Hospital Dr. Miguel Silva were analyzed. The percentages of graft failure were obtained. Kaplan-Meier survival analysis was performed to evaluate the long-term cumulative probability of graft non-rejection in all patients according to diagnosis.
Results:
Overall, 71.9% (CI 95%: 64.8-78.9) of the patients did not have any graft rejections, and 12.5% (CI 95%: 7-18) required a regraft and were considered graft failures. Patients with posttraumatic leucoma had a cumulative probability of non-rejection of 100%. Subjects with keratoconus had a 65% likelihood of non-rejection after 40 months of follow-up. The likelihood of non-rejection was greater than 80% at 100 months of follow-up in pseudophakic bullous keratopathy patients and 60% at 20 months of follow-up in inactive herpetic leucoma patients.
Conclusions:
Posttraumatic leucoma patients had the greatest cumulative survival probability compared with postherpetic leucoma patients and other patient groups.
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