Related Experiment Video
Updated: May 8, 2026

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
Published on: November 30, 2021
Sex-specific trends in under-five mortality in rural Ballabgarh
Anand Krishnan1, N G Nawi, Peter Byass
1Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India; *Umea Centre for Global Health Research, Department of Public Health and Clinical Medicine, Umea University, Sweden and #Department of Community Health, St. Stephens Hospital, Delhi, India. Correspondence to: Dr Anand Krishnan, Additional Professor, Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India. kanandiyer@yahoo.com.
Insights
Child survival in India shows significant gender disparities, with girls experiencing higher mortality rates post-neonatal and in childhood. Addressing neonatal mortality and gender inequities is crucial for reducing overall child deaths.
Area of Science:
- Demography
- Public Health
- Child Survival Research
Background:
- Child mortality remains a significant public health concern in India.
- Understanding sex-specific differentials in child survival is essential for targeted interventions.
Purpose of the Study:
- To assess sex-specific differentials in child survival between 1992 and 2011.
- To identify trends in under-five mortality rates and their relation to sex.
Main Methods:
- Analysis of data from the Health and Demographic Surveillance System (HDSS) in Ballabgarh, North India.
- Examination of sex ratio at birth and under-five mortality rates over a 20-year period.
Main Results:
- The sex ratio at birth consistently favored boys, with rates ranging from 821 to 866 girls per 1,000 boys.
- Under-five mortality rates stagnated due to a significant increase in neonatal mortality.
- Mortality rates were consistently higher for girls than boys in post-neonatal (160-200% higher) and childhood (160-230% higher) periods.
Conclusions:
- Neonatal mortality rates have increased, contributing to stagnant under-five mortality.
- Significant gender disparities exist in child survival, with girls facing higher risks.
- Targeted strategies addressing both neonatal mortality and gender inequities are necessary to reduce child mortality in India.
Objective:
To assess sex-specific differentials in child survival from 1992-2011.
Methods:
We analyzed data from the electronic database of Health and Demographic Surveillance System (HDSS) site in Ballabgarh in North India.
Results:
Sex ratio at birth was adverse for girls throughout the study period (821 to 866 girls per 1,000 boys) and was lowest in the period 2004-2006 at 821 girls per 1,000 boys. Overall, under-five mortality rates during the period 1992-2011 remained stagnant due to increasing neonatal mortality rate (9.2 to 27.7 P< 0.001). Mortality rates among girls were consistently and significantly higher than boys during the post-neonatal period (160% to 200% higher) as well as in childhood(160% to 230% higher).
Conclusions:
Strategies to address the neonatal mortality and gender differences are required for further reductions in child mortality in India.
Related Concept Videos
Applications of Life Tables
Life Tables
Lethal Alleles
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Bias in Epidemiological Studies
Relative Risk
Infertility in Males
