CHEF induced highly selective and sensitive turn-on fluorogenic and colorimetric sensor for Fe3+.
Shyamaprosad Goswami1, Sangita Das, Krishnendu Aich
1Department of Chemistry, Bengal Engg. and Science University, Shibpur, Howrah-711 103, India. spgoswamical@yahoo.com.
Dalton Transactions (Cambridge, England : 2003)
|September 4, 2013
Summary
A novel fluorescent probe for Fe(3+) detection was developed. This sensitive sensor shows a distinct color and fluorescence change, enabling accurate iron ion sensing in aqueous solutions.
Area of Science:
- Analytical Chemistry
- Materials Science
- Inorganic Chemistry
Background:
- Iron(III) (Fe3+) is crucial in biological systems but toxic at high levels.
- Sensing Fe3+ is vital for environmental monitoring and biological studies.
- Developing selective and sensitive probes for Fe3+ remains a challenge.
Purpose of the Study:
- To synthesize and characterize a new fluorescent probe for Fe3+ detection.
- To evaluate the probe's specificity, sensitivity, and response mechanism.
- To assess the probe's applicability in aqueous environments and practical sensing methods.
Main Methods:
- Synthesis of a rhodamine-6G derivative with 6-(hydroxymethyl) picolinohydrazide.
- Structural confirmation using single crystal X-ray diffraction.
- Spectroscopic analysis (absorbance and fluorescence) to determine sensing properties.
- Testing selectivity against various heavy and transition metal ions (HTMs).
Main Results:
- The probe exhibited high specificity and sensitivity for Fe3+.
- A visible colorimetric change (colorless to pink) and turn-on fluorescence (greenish-yellow) were observed.
- Significant enhancements in absorbance (116-fold) and emission (23-fold) were recorded.
- The limit of detection for Fe3+ was in the 10(-8) M range.
- The probe demonstrated effective performance in a 'dip stick' method.
Conclusions:
- The developed rhodamine-6G based probe is a highly effective tool for Fe3+ sensing.
- The probe's mechanism involves Fe3+-induced spirolactam ring opening.
- Its sensitivity, selectivity, and ease of use make it suitable for practical applications.
