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Leprosy treatment dropout: a systematic review
Régio José Santiago Girão1, Nara Lívia Rezende Soares, Juliana Viana Pinheiro
1Faculdade de Medicina do ABC, Santo André, SP, Brazil. regiogirao@hotmail.com.
International Archives of Medicine
|September 5, 2013
Summary
Leprosy treatment dropout is a significant public health issue in Brazil. Addressing socioeconomic factors, patient commitment, and healthcare integration is crucial for improving treatment adherence and controlling the disease.
Area of Science:
- Medical Science
- Public Health
- Infectious Diseases
Background:
- Leprosy remains a public health concern in Brazil, necessitating effective treatment and reduced dropout rates.
- Controlling leprosy transmission depends on consistent patient adherence to treatment regimens.
Purpose of the Study:
- To systematically review published studies on treatment dropout in leprosy patients.
- To identify factors contributing to treatment interruption and non-compliance in leprosy management.
Main Methods:
- Systematic review of articles published between January 2005 and April 2013.
- Searches conducted on MEDLINE and SciELO databases using specific MeSH terms and keywords related to leprosy and patient dropout.
Main Results:
- An initial 196 references were screened.
- A final sample of 20 articles was included after title and abstract analysis.
Conclusions:
- Leprosy non-compliance leads to continued infection, complications, and drug resistance.
- Factors influencing dropout include socioeconomic status, education, health service efficiency, and drug side effects.
- Improved professional-user integration and patient commitment are key to reducing leprosy treatment dropout.
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