Related Experiment Video
Updated: May 8, 2026
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
How to manage infected aortic endografts
1Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Perlman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
The Journal of Cardiovascular Surgery
|September 5, 2013
Summary
Aortic endograft infections, though rare at 0.6%, are increasing. Understanding their pathophysiology, diagnosis, and treatment, including traditional surgery and emerging less invasive options, is crucial for managing this complication.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Medical Device Complications
Background:
- Aortic endografts are standard for thoracic and infrarenal aortic aneurysms.
- Endograft infections occur in approximately 0.6% of cases.
- Increasing use of endografts leads to a rise in infection cases.
Purpose of the Study:
- To review the pathophysiology, diagnostic work-up, and treatment strategies for aortic endograft infections.
- To highlight the importance of understanding endograft infection management for physicians.
- To discuss both traditional and novel treatment approaches.
Main Methods:
- Literature review of endograft infections.
- Analysis of current treatment guidelines and emerging strategies.
- Discussion of pathophysiology and diagnostic modalities.
Main Results:
- Prolonged antibiotic therapy and surgical explant with bypass are current mainstays.
- Less invasive strategies are increasingly employed for high-risk patients.
- Understanding pathophysiology aids in effective management.
Conclusions:
- Aortic endograft infections require comprehensive management strategies.
- Both traditional and less invasive treatments have roles.
- Continued research into optimal management is warranted.
Related Concept Videos
01:18Endocarditis III: Medical Management
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
01:26Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
01:22Aneurysm IV: Nursing Management
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
01:29Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
01:25Endocarditis I: Introduction
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
01:25Aortic Regurgitation III: Medical Management
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...