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Updated: May 8, 2026
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Cardiac resynchronization therapy using a dual chamber pacemaker in patients with severe left ventricular dysfunction
Jae Jun Jung1, In Sook Kim, Jae-Han Jeong
1Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
The Korean Journal of Thoracic and Cardiovascular Surgery
|September 5, 2013
Summary
Dual chamber (DDD) pacing effectively improved cardiac output and resynchronization in a patient with coronary artery disease, left bundle branch block (LBBB), and severe left ventricle (LV) dysfunction post-coronary artery bypass grafting (CABG). This demonstrates DDD pacing
Area of Science:
- Cardiology
- Cardiac Electrophysiology
Background:
- Coronary artery disease (CAD) with severe left ventricle (LV) dysfunction and left bundle branch block (LBBB) presents significant management challenges.
- Post-coronary artery bypass grafting (CABG) patients may experience persistent electrical conduction abnormalities impacting cardiac output.
Observation:
- A 51-year-old female patient with three-vessel CAD, LBBB (QRS 166ms), and severe LV dysfunction underwent CABG.
- Postoperatively, DDD pacing with right atrial and biventricular leads was initiated to address conduction defects and enhance atrial activation.
Findings:
- Cardiac output increased from baseline (2.8-3.6 L/min) to 3.5-3.5 L/min with DDD pacing.
- Biventricular synchronization via DDD pacing was discontinued 18 hours post-surgery, with the patient maintaining improved cardiac output (3.9 L/min) upon transfer to the general ward.
Implications:
- DDD pacing can serve as a viable cardiac resynchronization therapy (CRT) strategy in select CAD patients with LBBB and LV dysfunction following CABG.
- This approach may optimize hemodynamic function and recovery in complex cardiac surgical patients.
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