Influences of gravitational stress and total muscle mass on human cardiovascular adjustments during prolonged dynamic...

To investigate cardiovascular adjustments to combined stress of gravity and exercise during dynamic exercise prolonged over 60 minutes in upright position, the three experiments were carried out. In Experiment I, as performing moderate upright bicycling (66% VO2 max) until exhaustion (average 86 minutes) in 4 trained men, changing manners of cardiovascular adjustments were shown in three phases, which were (1) regulating set-point body temperature, (2) making to maintain suitable blood pressure, and (3) failing to control the blood pressure. In Experiment II, as performing moderate supine cycling (55% VO2 max) for 50 minutes under several LBNP conditions in 5 sedentary women, there were correspondingly similar changing manners of the cardiovascular adjustments to each of the phases given in Experiment I. In Experiment III, as examining tolerance of orthostatic circulatory regulation, the tolerance was significantly correlated to VO2 max and lean body mass (LBM) (both p less than 0.05) in 8 sedentary women. When a moderate upright exercise is performed over 60 minutes in upright position, the performance should be influenced by total muscle mass indicated by LBM as well as by VO2 max, because the muscle mass could play a valuable role in the tolerance of orthostatic circulatory regulation vs. gravity.