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¹From the Departments of Radiology (A.S.K. e-mail: alisamikivrak@hotmail.com, Y.P., C.E., M.K., S.Ö.) and Public Health (F.K.), Selçuk University School of Medicine, Konya, Turkey.

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Summary

Apparent diffusion coefficient (ADC) values vary across different magnetic resonance imaging (MRI) vendors. Consider the MRI vendor when interpreting diffusion-weighted MRI (DW-MRI) results in clinical practice.

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Area of Science:

Radiology
Medical Imaging
Diffusion-Weighted MRI

Background:

Diffusion-weighted MRI (DW-MRI) is a valuable technique for assessing tissue microstructure.
Apparent diffusion coefficient (ADC) values are quantitative metrics derived from DW-MRI.
Standardization of ADC measurements across different MRI scanners is crucial for reliable clinical interpretation.

Purpose of the Study:

To compare apparent diffusion coefficient (ADC) values obtained from diffusion-weighted MRI (DW-MRI) examinations across multiple magnetic resonance imaging (MRI) scanners from different vendors.

Main Methods:

A custom phantom solution was used for DW-MRI examinations on six different 1.5 Tesla MR scanners (A-F) with consistent sequence parameters.
ADC maps were generated using b factors of 0 and 1000 s/mm(2).
ADC measurements were performed using regions of interest and various software programs, including postprocessing workstations, PACS, and operator console software.

Main Results:

Significant differences in ADC values were observed among the tested MRI scanners (P = 0.002).
Scanners A and F showed higher ADC values, while scanner B showed lower values compared to others.
Intra-vendor differences in ADC values were statistically significant (P < 0.001), though differences between scanners C and E were not significant (P = 0.15).

Conclusions:

Apparent diffusion coefficient (ADC) values can exhibit variability depending on the magnetic resonance imaging (MRI) vendor and system used.
The findings highlight the importance of considering the MRI vendor when interpreting DW-MRI data in clinical settings.
Further standardization efforts are needed to ensure consistency in ADC measurements across different MRI platforms.