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Spectrophotometric determination of oxprenolol hydrochloride as its Fe (III) complex
D Radulović1, D Pećanac, L Zivanović
1Institute of Pharmaceutical Chemistry, Faculty of Pharmacy, Belgrade, Yugoslavia.
Farmaco (Societa Chimica Italiana : 1989)
|April 1, 1990
Abstract:
A spectrophotometric determination of oxprenolol hydrochloride in pharmaceutical preparations is described. The method is based on the reaction of oxprenolol hydrochloride with Fe (III) ion in the presence of ammonium thiocyanate, in acid media. The complex formed between oxprenolol hydrochloride and Fe (III) ion was extracted with chloroform and assayed spectrophometrically at 477 nm. The results obtained are reproducible and hence the method is suitable for the determination of oxprenolol hydrochloride in pharmaceutical dosage forms.