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Griseofulvin-induced protoporphyria revisited
O A Gederaas1, O L Brekke, I Romslo
1Department of Clinical Chemistry, University of Trondheim, University Hospital, Norway.
Photodermatology, Photoimmunology & Photomedicine
|April 1, 1990
Abstract:
In nude mice grieofulvin given by intraperitoneal injections produces a severe porphyric state within 1 week. Compared with peroral administration of griseofulvin to produce experimental porphyria, this model is much more efficient and can be more easily controlled.
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