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Related Experiment Video

Updated: May 8, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

[Renal denervation 2013].

J Spinar¹, J Vítovec, L Spinarová

¹Interni kardiologicka klinika Lekarske fakulty MU a FN Brno. jspinar@fnbrno.cz

Vnitrni Lekarstvi

|September 7, 2013

Summary

This summary is machine-generated.

Resistant hypertension, a common clinical issue, can be effectively managed with renal denervation. This procedure uses catheter radiofrequency ablation to reduce high blood pressure in patients unresponsive to medication.

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Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

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Last Updated: May 8, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

Published on: June 6, 2025

Area of Science:

Cardiology
Nephrology
Interventional Radiology

Background:

Arterial hypertension affects 30-40% of adults globally.
Resistant hypertension is defined by persistent high blood pressure despite medication.
It poses a significant clinical challenge worldwide.

Purpose of the Study:

To evaluate the efficacy and safety of renal denervation for resistant hypertension.
To review current data and future applications of the procedure.
To provide an overview of existing and developing renal denervation devices.

Main Methods:

Renal denervation involves catheter radiofrequency ablation of renal artery sympathetic nerves.
The Symplicity HTN-1 and HTN-2 trials demonstrated its effectiveness.
This invasive method targets the autonomic nervous system's role in hypertension.

Main Results:

Renal denervation demonstrated a safe and significant decrease in blood pressure.
The procedure proved effective in patients with resistant hypertension.
Positive outcomes were observed in key clinical trials.

Conclusions:

Renal denervation is a promising therapeutic option for resistant hypertension.
Further research is needed to confirm findings and explore future applications.
The procedure offers a new avenue for managing difficult-to-treat hypertension.