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Published on: August 13, 2019
Predictors of cardiovascular risk in women
1David Geffen School of Medicine, Division of Cardiology, Department of Medicine, University of California-Los Angeles, 650 Charles E Drive South, Los Angeles, CA 90095 1679, USA.
Insights
Cardiovascular disease remains a leading cause of death for women. Early risk stratification and aggressive management of modifiable risk factors are crucial for improving women's cardiovascular health outcomes.
Area of Science:
- Cardiology
- Women's Health
- Preventive Medicine
Background:
- Cardiovascular disease (CVD) is the primary cause of mortality in women, accounting for one in three female deaths.
- Despite advancements, significant gender and ethnic disparities persist in cardiovascular outcomes.
- The decline in heart disease mortality is slower in women compared to men, indicating a need for targeted interventions.
Purpose of the Study:
- To emphasize the critical need for improved cardiovascular disease (CVD) outcomes in women.
- To recommend strategies for risk stratification and management of modifiable risk factors in women.
- To highlight the necessity of gender-specific approaches to address the CVD outcomes gap.
Main Methods:
- This study is a review and recommendation based on existing data and clinical guidelines.
- It synthesizes current knowledge on CVD risk factors and outcomes in women.
- Recommendations are based on established evidence for risk stratification and factor modification.
Main Results:
- Cardiovascular disease (CVD) poses a significant long-term risk for all women.
- Aggressive modification of risk factors such as lipid abnormalities, hypertension, smoking, diabetes, obesity, and physical inactivity is essential.
- Inflammatory markers may also play a role in CVD risk for women.
Conclusions:
- Every woman should undergo comprehensive cardiovascular risk stratification for both short-term and lifetime risk.
- Intensive management of modifiable cardiovascular risk factors is paramount for all women.
- Gender-specific interventions are vital to close the cardiovascular outcomes gap between men and women.
Abstract:
Cardiovascular disease is the leading cause of death in women, contributing to one in three female deaths. Despite improvements in overall cardiovascular outcomes, substantial gender and ethnic disparities remain. In order to improve outcomes among women, we recommend the following: every woman should undergo risk stratification for short-term and lifetime cardiovascular risk given the substantial long-term risk of cardiovascular disease; modifiable cardiovascular risk factors in women should be modified to the greatest extent possible; and these factors include lipid abnormalities, hypertension, smoking, diabetes, obesity, physical inactivity and, possibly, inflammatory markers. The rate of decline in heart disease is slower for women than men, highlighting the need for gender-specific interventions to address the outcomes gap.
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