Related Experiment Video
Updated: May 8, 2026
05:59
Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
Published on: March 7, 2019
[Physical activity and cancer survival]
Isabelle Romieu1, Marina Touillaud, Pietro Ferrari
1International Agency for Research on Cancer, 150, cours Albert-Thomas, 69372 Lyon cedex 08, France.
Bulletin Du Cancer
|September 7, 2013
Summary
Physical activity benefits cancer survivors by improving survival rates and quality of life. Further research is needed to standardize interventions for definitive survival conclusions.
Area of Science:
- Oncology
- Exercise Science
- Epidemiology
Background:
- Large cohort studies indicate physical activity improves cancer survivor survival.
- Randomized controlled trials (RCTs) suggest benefits for fitness, quality of life, and mental well-being.
- Limitations in existing RCTs include small sample sizes, short follow-up, and inconsistent intervention protocols, hindering definitive survival conclusions.
Framework:
- A workshop convened at the International Agency for Research on Cancer (IARC) in April 2011.
- Focused on the role of physical activity in cancer survival.
- Addressed methodologies for developing multicenter randomized intervention trials.
Implementation:
- Discussed optimal types of physical activity interventions.
- Explored the integration of physical activity with nutritional recommendations.
- Emphasized the need for standardized protocols in future trials.
Implications:
- Physical activity influences cancer survival through mechanisms like reduced adiposity, lower estrogen levels, and improved insulin sensitivity.
- Findings have particular relevance for breast cancer survivors.
- The workshop's conclusions guide future research toward robust, multicenter trials to confirm physical activity's impact on cancer survival.
More Related Videos
Related Concept Videos
02:59Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
02:59Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
01:21Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
03:03mTOR Signaling and Cancer Progression
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
The mTOR pathway or the...
01:20Actuarial Approach
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
01:20Comparing the Survival Analysis of Two or More Groups
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and Cox...