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Updated: May 8, 2026

Intrasplenic Transplantation of Hepatocytes After Partial Hepatectomy in NOD.SCID Mice
Published on: February 10, 2018
[Current status and future perspectives of hepatocyte transplantation]
Eugenia Pareja1, Miriam Cortés2, M José Gómez-Lechón3
1Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante Hepático, Hospital Universitario La Fe de Valencia, Valencia, España; Unidad de Terapia Celular Hepática, Hospital Universitario La Fe de Valencia, Valencia, España.
Abstract:
The imbalance between the number of potential beneficiaries and available organs, originates the search for new therapeutic alternatives, such as Hepatocyte transplantation (HT).Even though this is a treatment option for these patients, the lack of unanimity of criteria regarding indications and technique, different cryopreservation protocols, as well as the different methodology to assess the response to this therapy, highlights the need of a Consensus Conference to standardize criteria and consider future strategies to improve the technique and optimize the results.Our aim is to review and update the current state of hepatocyte transplantation, emphasizing the future research attempting to solve the problems and improve the results of this treatment.

