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Updated: May 8, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis
Published on: August 15, 2025
Antioxidant xanthones from Swertia mussotii, a high altitude plant
Cui-Ting Luo1, Shuang-Shuang Mao1, Fang-Lan Liu1
1Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China.
Abstract:
Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-β-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(β-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(β-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(β-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where 1 is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed.
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