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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

An unusual cause of ischemic stroke with successful thrombolysis

Giovanni Corrado1, Paolo Panisi, Nicoletta Checcarelli

  • 1Department of Cardiology, Ospedale Valduce, Como, Italy.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|September 7, 2013
PubMed

A 63-year-old woman was admitted because of sudden ischemic hemyplegia promptly cleared up by intravenous (IV) recombinant tissue plasminogen activator. On subsequent 2-dimensional echocardiogram, we observed an extremely mobile homogeneous mass attached by a short stalk to ventricular insertion of anterolateral papillary muscle chordae tendineae. The mass was surgically removed. Gross anatomy showed a mass with a gelatinoids appearance formed on histology by a lining of hyperplastic endocardial cells covering a hypocellular stroma consistent with papillary fibroelastoma. Given the prompt clinical improvement with IV thrombolytic therapy, we postulate that cerebral artery occlusion was at least in part because of thrombotic material.

Keywords:
Cardiac source of embolismechocardiographypapillary fibroelastomastroke

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