Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The 4th Educational Course of the European Burns Association (EBA).

European burn journal·2026
Same author

Ventricle Width and Cerebrospinal Fluid Diversion Rate after Open Fetal Spina Bifida Repair: A 4-Year Follow-Up.

Fetal diagnosis and therapy·2026
Same author

Safety and efficacy of bio-engineered, autologous dermo-epidermal skin grafts in reconstructive surgery: 1-year results of a prospective, randomized, intra-patient controlled, multicenter phase II clinical trial.

Journal of tissue engineering·2026
Same author

Safety and efficacy of bio-engineered, autologous dermo-epidermal skin grafts in adolescent and adult burn patients: 1-year results of a prospective, randomized, controlled, multicenter phase IIB clinical trial.

EClinicalMedicine·2025
Same author

Multisource feedback in residency training: A quantitative study to investigate the feedback conversation.

GMS journal for medical education·2025
Same author

Normalization of the Middle Cerebral Artery Resistance Index: A Sign for Adequate Untethering of the Spinal Cord and Regression of Hindbrain Herniation after Fetal Spina Bifida Repair?

Fetal diagnosis and therapy·2025

Related Experiment Videos

Management of "difficult" wounds.

Kathrin Neuhaus1, Martin Meuli, Ingo Koenigs

  • 1Pediatric Burn Centre, Division of Plastic and Reconstructive Surgery, Department of Surgery, University Children's Hospital Zurich, Zurich, Switzerland.

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [Et Al] = Zeitschrift Fur Kinderchirurgie
|September 7, 2013
PubMed
Summary

Managing pressure sores (PSs) and wounds in immunocompromised children requires individualized care. Surgical closure is often necessary for rapid healing and preventing severe complications in these vulnerable patients.

Related Experiment Videos

Area of Science:

  • Pediatric Plastic Surgery
  • Wound Healing
  • Immunocompromised Patients

Background:

  • Pressure sores (PSs) and wounds are rare but complex conditions in immunocompromised children.
  • Standardized care algorithms are lacking, necessitating individualized therapeutic approaches.
  • Impaired wound healing and low host defense increase infection and septic complication risks.

Purpose of the Study:

  • To outline effective management strategies for pressure sores and wounds in immunocompromised children.
  • To emphasize the importance of prevention and timely surgical intervention.
  • To discuss optimal surgical techniques and adjunctive therapies.

Main Methods:

  • Review of current literature and clinical experience in managing PSs and wounds in pediatric patients.
  • Discussion of primary and secondary prevention strategies.
  • Evaluation of surgical techniques including skin grafts, local flaps, and negative pressure wound therapy (NPWT).

Main Results:

  • Successful PS management hinges on pressure relief and prevention.
  • Surgical closure, particularly with full-thickness skin grafts and local flaps, is often mandatory when conservative care fails.
  • NPWT is crucial for wound bed preparation prior to definitive closure.
  • High recurrence rates are linked to unaddressed pathogenic factors, not surgical technique alone.
  • Rapid, definitive wound closure is essential in immunocompromised children to prevent sepsis.

Conclusions:

  • Individualized treatment plans are critical for PSs and wounds in immunocompromised children.
  • Surgical intervention is frequently required for optimal outcomes.
  • Addressing underlying pathogenic factors is key to minimizing recurrence.