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Pharmaconutrition review: physiological mechanisms.

Joseph F Pierre1, Aaron F Heneghan, Christy M Lawson

  • 1Veterans Administration Surgical Services, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin.

JPEN. Journal of Parenteral and Enteral Nutrition
|September 7, 2013
PubMed
Summary
This summary is machine-generated.

Pharmaconutrition uses specific nutrients to enhance immune defenses and improve outcomes for critically ill patients. This review explores the physiological mechanisms of key pharmaconutrients like glutamine and omega-3 fatty acids.

Keywords:
immune modulationimmunonutritionnutrition therapypharmaconutrition

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Area of Science:

  • Critical care medicine
  • Nutritional science
  • Immunology

Background:

  • Nutrition support is crucial for critically ill patients.
  • Enhancing host defenses is a key therapeutic goal.
  • Pharmaconutrition investigates specific nutrients for therapeutic effects.

Purpose of the Study:

  • To review the physiological mechanisms of pharmaconutrients.
  • To highlight the role of specific nutrients in critical care.
  • To understand the impact of pharmaconutrients on immune and clinical outcomes.

Main Methods:

  • Literature review of pharmaconutrition studies.
  • Focus on physiological and immunological effects.
  • Analysis of key nutrients: glutamine, arginine, omega-3 fatty acids, and selenium.

Main Results:

  • Pharmaconutrients modulate immune responses.
  • Specific nutrients have distinct physiological actions.
  • Evidence suggests potential benefits in clinical outcomes.

Conclusions:

  • Pharmaconutrition represents a targeted approach to nutritional therapy.
  • Understanding nutrient mechanisms is vital for optimizing patient care.
  • Further research is needed to fully elucidate clinical benefits.