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A Case of Small Bowel Ulcer Associated with Helicobacter pylori
Eun Young Kim1, Ji Hyun Kim, Saet Byul Woo
1Department of Pediatrics, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
Insights
Helicobacter pylori can cause rare small bowel ulcers in children, even without other diseases. Eradicating H. pylori effectively treated a young patient's abdominal pain and ulcers.
Area of Science:
- Pediatric Gastroenterology
- Microbiology
- Digestive Diseases
Background:
- Peptic ulcer disease in children is often linked to Helicobacter pylori (H. pylori) or underlying conditions.
- H. pylori typically causes duodenal bulb ulcers, as bile inhibits its growth lower in the small intestine.
- Small bowel ulcers associated with H. pylori are infrequently reported.
Observation:
- A case study involved an 11-year-old girl presenting with multiple small bowel ulcerative lesions.
- The patient had no identifiable systemic diseases.
- Esophagogastroduodenoscopy revealed lesions in the proximal jejunum.
Findings:
- Multiple small bowel ulcerative lesions were found to be associated with H. pylori infection.
- The patient's abdominal pain resolved following H. pylori eradication therapy.
- This case highlights a rare presentation of H. pylori-associated small bowel ulceration.
Implications:
- This case expands the known spectrum of H. pylori-related gastrointestinal pathology in pediatric patients.
- It underscores the importance of considering H. pylori in pediatric cases of small bowel ulcers, even when atypical.
- Further research may clarify the mechanisms and prevalence of H. pylori in the small bowel.
Abstract:
The etiology of peptic ulcer disease in children may be primary, associated with Helicobacter pylori infection, or secondary, relied on underlying disease. Ulcerative lesions by H. pylori are mainly distributed in the duodenal bulb and they are rare below the ampulla of Vater because H. pylori growth is inhibited by bile juice. In this reason, there are only some restrictive reports presented small bowel ulcer associated H. pylori. We found multiple small bowel ulcerative lesions associated with H. pylori in an 11-year-old girl without any systemic disease while performing esophagogastroenteroscopy to the level of the proximal jejunum for differentiating bezoar. The abdominal pain improved after the patient was administered H. pylori eradication therapy. Because a small bowel ulcer associated with H. pylori has rarely been reported, we report it here with literature review.
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