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Decrease of brain zinc in experimental hepatic encephalopathy

M Baraldi1, E Caselgrandi, P Borella

  • 1University of Modena, 41100 Modena, Italy.

Brain Research
|September 10, 2013
PubMed

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Hepatic Encephalopathy01:29

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...