Related Experiment Video
Updated: May 8, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
[Formulation optimization of ginkgo flavonoids matrix tablets by orthogonal design]
Ying-Xin Guo1, Fei Li, Qian-Qian Zhao
1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. guoyingxin2010@126.com
Researchers developed sustained-release ginkgo flavonoids matrix tablets to improve cardiovascular and cerebrovascular disease treatment. This formulation overcomes limitations of conventional ginkgo preparations, offering enhanced drug delivery and therapeutic benefits.
Area of Science:
- Pharmaceutical Sciences
- Drug Delivery Systems
- Pharmacology
Background:
- Conventional ginkgo preparations exhibit shortcomings in treating cardiovascular and cerebrovascular diseases.
- Sustained-release formulations offer unique advantages for drug delivery and therapeutic efficacy.
Purpose of the Study:
- To prepare ginkgo flavonoids matrix tablets with sustained-release properties.
- To investigate and optimize the formulation of these sustained-release tablets.
- To elucidate the drug release mechanism of the developed ginkgo flavonoids matrix tablets.
Main Methods:
- Preparation of ginkgo flavonoids matrix tablets.
- Investigation of matrix material, adhesives, and fillers.
- Optimization of formulation using orthogonal design.
- Analysis of drug release kinetics using Zero-order, First-order, Higuchi, and Ritger-Peppas models.
Main Results:
- Successful preparation of ginkgo flavonoids matrix tablets.
- Identification of optimal formulation parameters through orthogonal design.
- Characterization of drug release profiles and mechanisms.
Conclusions:
- Ginkgo flavonoids matrix tablets offer a promising approach for sustained drug delivery.
- The developed formulation effectively addresses limitations of conventional ginkgo preparations.
- Understanding drug release kinetics is crucial for optimizing therapeutic outcomes.
More Related Videos
09:12Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method
Published on: May 19, 2023
06:00Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development
Published on: March 17, 2023
Related Concept Videos
Methods of Medium Optimization
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules
Factors Influencing Drug Absorption: Pharmaceutical Parameters
Dosage Regimen Designs: Nomograms and Tabulations
Dosage Regimens: Designs and Approaches
Biopharmaceutical Factors Influencing Drug Product Design: Overview