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Updated: May 8, 2026
09:51
Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
How community has shaped the Protein Data Bank
Helen M Berman1, Gerard J Kleywegt, Haruki Nakamura
1RCSB PDB, Center for Integrative Proteomics Research and Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ USA 08854.
Structure (London, England : 1993)
|September 10, 2013
Summary
The Protein Data Bank (PDB), established in 1971, is a vital public archive for macromolecular structures. It has grown with structural biology, ensuring data quality and accessibility for researchers worldwide.
Area of Science:
- Structural Biology
- Biochemistry
- Bioinformatics
Background:
- The Protein Data Bank (PDB) was founded in 1971.
- It serves as a public repository for 3D structural models of biological macromolecules.
- The PDB has evolved alongside the growth in structural biology.
Purpose of the Study:
- To provide an overview of the PDB's history.
- To highlight the PDB's role in managing and disseminating structural data.
- To emphasize the community's ongoing influence on the PDB archive.
Main Methods:
- Historical review of the Protein Data Bank.
- Analysis of PDB's growth in data quantity and complexity.
- Description of PDB's management by the Worldwide PDB organization.
Main Results:
- The PDB has successfully met increasing demands for structural information.
- The archive has grown in the number, size, and complexity of models.
- The PDB promotes data standards and raises the profile of structural biology.
Conclusions:
- The PDB is a dynamic resource shaped by community input.
- It provides unrestricted access to crucial structural data.
- The PDB continues to be essential for advancing structural biology research.
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