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Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

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PET/computed tomography and lymphoma.

Martin Allen-Auerbach¹, Sven de Vos, Johannes Czernin

¹Ahmanson Translational Imaging Division/Nuclear Medicine, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095-6948, USA.

Radiologic Clinics of North America

|September 10, 2013

Summary

¹⁸F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scans are crucial for assessing lymphoma. FDG-PET/CT reliably evaluates lymphoma metabolic activity, aiding in staging and treatment monitoring.

Keywords:

FDG Lymphoma PET PET/CT

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Murine Lymphocyte Labeling by 64Cu-Antibody Receptor Targeting for In Vivo Cell Trafficking by PET/CT

Murine Lymphocyte Labeling by ⁶⁴Cu-Antibody Receptor Targeting for In Vivo Cell Trafficking by PET/CT

Published on: April 29, 2017

Area of Science:

Oncology
Nuclear Medicine
Radiology

Background:

¹⁸F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) integrates PET and CT imaging.
Lymphomas often exhibit high glucose metabolism and FDG uptake.
FDG-PET/CT is increasingly utilized in lymphoma management.

Purpose of the Study:

To highlight the role of FDG-PET/CT in assessing lymphoma.
To emphasize its diagnostic capabilities for staging, restaging, and treatment monitoring.

Main Methods:

Utilizing FDG-PET/CT for imaging patients with lymphoma.
Assessing metabolic activity and FDG avidity of lymphomas.

Main Results:

FDG-PET/CT reliably assesses lymphoma metabolic activity.
The modality demonstrates high sensitivity and specificity for staging and restaging.
PET/CT is effective for treatment monitoring in lymphoma patients.

Conclusions:

FDG-PET/CT is the preferred imaging modality for lymphoma assessment.
Its ability to characterize masses and monitor treatment response is vital for patient management.