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Xylitol lozenges were not effective in overall dental caries prevention in adults
Margherita Fontana1, Carlos Gonzalez-Cabezas
1Associate Professor, Department of Cariology, Restorative Sciences and Endodontics, University of Michigan School of Dentistry, 1011 N University, Ann Arbor, MI 48109, USA.
Article Title And Bibliographic Information:
Results from the xylitol for adult caries trial (X-ACT). Bader JD, Vollmer WM, Shugars DA, Gilbert GH, Amaechi BT, Brown JP, Laws RL, Kunkhouser KA, Makhija SK, Ritter AV, Leo MC. JADA 2013; 144(1): 21-30.
Reviewers:
Margherita Fontana, DDS, PhD, Carlos Gonzalez-Cabezas, DDS, MSD, PhD PURPOSE/QUESTION: Among an adult population at risk of dental caries, does the use of five 1 g xylitol lozenges per day over 33 months reduce the experience of cavitated caries lesions?
Source Of Funding:
Government: National Institute of Dental and Craniofacial Research
Type Of Study/Design:
Multicenter, double blind, placebo-controlled, randomized clinical trial
Level Of Evidence:
Level 1: Good quality, patient-oriented evidence
Strength Of Recommendation Grade:
B: Limited quality patient-oriented evidence.
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