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Updated: May 8, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
The combined use of chlorhexidine and fluoride therapy can reduce the risk for dental caries
1Assistant Professor, Department of Restorative Dental Sciences, Division of Operative Dentistry, College of Dentistry, University of Florida, 1395 Center Drive, Room D9-6, PO Box 100415, Gainesville, FL 32610-0415, USA. Tel.: +1 352 273 5858; fax: +1 352 846 1643.
Article Title And Bibliographic Information:
A randomized clinical trial of anticaries therapies targeted according to risk assessment (caries management by risk assessment). Featherstone JDB, White JM, Hoover CI, Rapozo-Hilo M, Weintraub JA, Wilson RS, Zhan L, Gansky SA. Caries Res 2012;46(2):118-29.
Reviewer:
Marcelle M. Nascimento, DDS, MS, PhD PURPOSE/QUESTION: The study sought to determine whether the use of preventive and restorative therapies based on individual caries risk for 2 years could reduce caries increment compared to traditional dental care provided at the University of California, San Francisco School of Dentistry (UCSF) SOURCE OF FUNDING: The main research support was provided by NIH/NIDCR and the oral products used in the study were provided by Proctor and Gamble, Omnii Oral Pharmaceuticals and Oral B TYPE OF STUDY/DESIGN: Randomized controlled trial
Level Of Evidence:
Level 1: Good-quality, patient-oriented evidence
Strength Of Recommendation Grade:
Not applicable.
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