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Related Experiment Video

Updated: May 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

A hyperpigmented perianal nodule.

Steven Kahn¹, Michael A Warso, Iris K Aronson

¹Department of Dermatology, University of Illinois, Chicago, IL, United States.

Dermatology Online Journal

|September 10, 2013

Summary

This summary is machine-generated.

Basal cell carcinoma (BCC), a common skin cancer, rarely occurs in the perianal region. This case highlights the need to consider non-solar factors for BCCs in unusual locations, as it was found during a colonoscopy.

Related Experiment Videos

Last Updated: May 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

Dermatology
Gastroenterology
Oncology

Background:

Basal cell carcinoma (BCC) is the most common human malignancy, primarily linked to ultraviolet (UV) radiation exposure.
Most BCCs develop on sun-exposed skin, with fewer than 1% occurring in the perianal or genital regions.

Observation:

This report details an exceptionally rare instance of BCC initially identified during a standard colonoscopy examination.
The patient presented with a BCC in the perianal region, an atypical location for this type of skin cancer.

Findings:

The diagnosis of basal cell carcinoma was confirmed in the perianal area.
This case underscores that etiological factors beyond solar exposure should be considered for BCCs in non-sun-exposed sites.

Implications:

This case challenges the traditional understanding of BCC etiology, suggesting non-UV-related factors may play a role in perianal BCC development.
Further investigation into alternative risk factors for BCC in rare anatomical locations is warranted.
Routine colonoscopy may offer an opportunity for early detection of BCC in the perianal region.