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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
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Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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Related Experiment Video

Updated: May 8, 2026

Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow
09:41

Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow

Published on: March 15, 2021

Functional imaging of cerebral perfusion.

A Krainik1, M Villien, I Troprès

  • 1Clinique universitaire de neuroradiologie et IRM, CHU de Grenoble, CS 10217, 38043 Grenoble cedex, France; Inserm U836, université Joseph-Fourier, site santé, chemin Fortuné-Ferrini, 38706 La Tronche cedex, France; UMS IRMaGe, unité IRM 3T recherche, CHU de Grenoble, CS 10217, 38043 Grenoble cedex 9, France.

Diagnostic and Interventional Imaging
|September 10, 2013
PubMed
Summary

Functional perfusion imaging studies blood flow regulation and neurovascular coupling. This technique assesses vascular reserve and ischemia risk, aiding therapeutic strategies for conditions like Alzheimer's disease and epilepsy.

Keywords:
ASLAutoregulationBOLDCBFCBVCVRCerebral perfusionCerebral vasoreactivityFunctional BOLD MRIMRANeurovascular couplingP(a)CO(2)P(e)CO(2)arterial pressure in CO(2)arterial spin labelingblood oxygenation level dependentcerebral blood flowcerebral blood volumecerebral vasoreactivityexpiratory pressure in CO(2)fMRIfunctional MRImagnetic resonance angiography

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Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia
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Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia

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Published on: March 15, 2021

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia
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Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia

Published on: September 20, 2015

Area of Science:

  • Neuroimaging
  • Medical Physics
  • Cardiovascular Physiology

Background:

  • Functional perfusion imaging offers insights into cerebrovascular dynamics.
  • Understanding vasoreactivity, autoregulation, and neurovascular coupling is crucial for diagnosing neurological disorders.

Purpose of the Study:

  • To explore the applications of functional perfusion imaging in studying hemodynamic disorders.
  • To evaluate its role in assessing vascular reserve and ischemia risk.
  • To enhance the interpretation of functional MRI in clinical research and practice.

Main Methods:

  • Utilizing functional imaging techniques to assess perfusion.
  • Analyzing vasoreactivity to circulating gases.
  • Estimating vascular reserve downstream from arterial stenosis.

Main Results:

  • Functional perfusion imaging reveals hemodynamic disorders in Alzheimer's disease and epilepsy patients with arteriovenous malformations.
  • The method quantifies vasoreactivity, autoregulation, and neurovascular coupling.
  • It aids in estimating vascular reserve and ischemia risk for therapeutic strategy adaptation.

Conclusions:

  • Functional perfusion imaging is a valuable tool for studying cerebrovascular function.
  • It aids in diagnosing and managing neurological conditions associated with hemodynamic dysfunction.
  • This technique improves the interpretation of functional MRI findings in research and clinical settings.