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Updated: May 8, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
Substance abuse and psychosis
Danielle Goerke1, Sanjiv Kumra
1Division of Child and Adolescent Psychiatry, University of Minnesota Medical School, F256/2B West, 2450 Riverside Avenue, Minneapolis, MN 55454, USA.
This review addresses key challenges in adolescent mental health, highlighting psychoeducation, family engagement, and antipsychotic medication. It emphasizes reducing cannabis use due to its potential role in psychosis and discusses substance abuse treatment for adolescents.
Area of Science:
- Psychiatry and Adolescent Mental Health
Background:
- Adolescents present unique diagnostic and treatment challenges in mental health care.
- Effective interventions require a multi-faceted approach tailored to this developmental stage.
Observation:
- Psychoeducation, active patient and family engagement, and judicious use of antipsychotic medications are crucial.
- Cannabis use is identified as a potential causal risk factor for psychotic illness in adolescents.
Findings:
- Reducing or ceasing cannabis consumption is recommended for adolescents at risk of or experiencing psychotic illness.
- Treatment strategies successful in adults may also be effective for adolescent substance abuse cessation post-psychosis.
Implications:
- This review informs clinical practice for adolescent psychiatric disorders and substance use.
- Further research into cannabis's role in adolescent psychosis and effective interventions is warranted.
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