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Tracking immune cells in vivo using magnetic resonance imaging

Eric T Ahrens1, Jeff W M Bulte

  • 1Department of Radiology, University of California at San Diego, San Diego, California 92093-0695, USA.

Nature Reviews. Immunology
|September 10, 2013
PubMed
Summary

Magnetic resonance imaging (MRI) advances immune cell tracking in vivo. New MRI probes enable detailed visualization of cell behavior and therapeutic responses, revolutionizing cellular therapies.

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...