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Published on: March 24, 2020
Spinal dysraphism
Insights
Significant advancements in managing spinal dysraphism have improved children's quality of life. Prevention strategies like food fortification are decreasing spina bifida rates, while prenatal imaging and surgical techniques offer new hope.
Area of Science:
- Neurology
- Pediatric Surgery
- Medical Imaging
Background:
- Spinal dysraphism management has seen major improvements over the past decade, enhancing children's quality of life.
- Global food fortification practices are reducing the incidence of spina bifida and myelomeningocele.
- Prenatal Magnetic Resonance (MR) imaging provides unprecedented detail, aiding early diagnosis and management planning.
Discussion:
- Intrauterine myelomeningocele closure shows variable results but holds promise for future experimental therapies.
- Neuropathic bladder management has advanced, becoming crucial for long-term patient follow-up.
- Micro-neurosurgical techniques and intraoperative monitoring have significantly improved outcomes for spinal cord tethering surgery.
Key Insights:
- Decreased incidence of myelomeningocele due to widespread food fortification.
- Enhanced prenatal diagnostics through advanced MR imaging.
- Improved surgical success rates for spinal cord untethering.
Outlook:
- Continued progress in intrauterine fetal surgery for myelomeningocele is anticipated.
- Intraoperative neurophysiological monitoring is expected to become standard practice in spinal cord surgeries.
- Further advancements in antenatal imaging and neuropathic bladder management are foreseen.
Abstract:
In the last decade there have been significant improvements in all the fields of management of patients with spinal dysraphism, which have increased dramatically the quality of life of these children. Prevention of spina bifida with food fortification is becoming increasingly practiced worldwide. As result, in many parts of the world the frequency of myelomeningocele has decreased. Intrauterine closure of myelomeningocele has been attempted in many institutions with variable results. While it is still at the sphere of experimental therapy, it is reasonable to anticipate progress in this field in the next decade. Antenatal MR imaging is already providing very high level of detail even before the child is born. This creates new ethical dilemmas and requires additional care, but has improved significantly the overall management of patients and their families. Further improvements are anticipated in this field. Management of neuropathic bladder has improved significantly in the last decade and is anticipated to play an increasing role in the long term follow up. Surgery for spinal cord tethering in all its forms has improved in the last decade, with far more chances of complete untethering now in comparison to 10-15 years ago, with the use of micro-neurosurgical techniques and intraoperative monitoring. It is reasonable to expect that in the next decade, intraoperative neurophysiological monitoring during spinal cord surgery will become mandatory. In the 2013 Annual Special Issue we have assembled a team of authors distinguished in their fields, who bring us up to date with all the latest developments.
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