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Updated: May 8, 2026
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Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
Published on: March 17, 2023
The use of an engineered single chain variable fragment in a localized surface plasmon resonance method for analysis
Ju-Young Byun1, Yong-Beom Shin, Taihua Li
1Department of Chemistry, School of Physics and Chemistry and Advanced Photonics Research Institute, Gwangju Institute of Science and Technology (GIST), Korea. mkim@gist.ac.kr.
Chemical Communications (Cambridge, England)
|September 10, 2013
Abstract:
A gold nanorod (GNR) based LSPR sensor has been developed for label-free detection of C-reactive protein (CRP). The sensor utilizes a single chain variable fragment (scFv) as a receptor to bind CRP. The results of this effort show that CRP in human serum can be quantitatively detected at lower than 1 ng mL(-1).
