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Related Experiment Video

Updated: May 8, 2026

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe
06:16

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe

Published on: March 1, 2022

Comparative study concerning mistletoe viscotoxins antitumor activity.

Roxana Liana Stan1, Adriana Corina Hangan, Lucia Dican

  • 1"Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca Department of Pharmaceutical Biochemistry and Clinical Laboratory, Faculty of Pharmacy 4/6 Pasteur Street 400012 Cluj-Napoca Romania.

Acta Biologica Hungarica
|September 10, 2013
PubMed
Summary

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Viscum album extract enhances doxorubicin

Area of Science:

  • Phytomedicine
  • Cancer Research
  • Oxidative Stress Biology

Background:

  • Viscum album L. (Santalaceae) exhibits anticancer properties.
  • Oxidative stress plays a role in tumor cell cytotoxicity.
  • Cytostatic therapies like doxorubicin are standard cancer treatments.

Purpose of the Study:

  • To investigate the role of oxidative stress in Viscum album-induced cytotoxicity.
  • To evaluate the combined effects of Viscum album extract and doxorubicin on tumor cells.
  • To assess the impact on antioxidant status in cancer models.

Main Methods:

  • Ehrlich ascites carcinoma (EAC) model in Swiss female mice.
  • Administration of Viscum album ethanolic extract and doxorubicin.
  • Analysis of tumor proliferation parameters and plasma antioxidant enzymes.

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Last Updated: May 8, 2026

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe
06:16

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe

Published on: March 1, 2022

Main Results:

  • Viscum album extract combined with doxorubicin improved protective effects against tumor growth.
  • Doxorubicin alone reduced ascitic fluid accumulation and plasma antioxidant enzyme activity.
  • Ehrlich tumor cells showed decreased catalase and increased xanthine oxidase/peroxidase activity.

Conclusions:

  • Viscum album extract potentiates the efficacy of doxorubicin in cancer therapy.
  • The combination therapy influences oxidative stress markers in tumor-bearing mice.
  • Viscum album demonstrates potential as an adjuvant in cancer treatment.