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Updated: May 8, 2026
04:17
Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices
Published on: March 8, 2024
Neocortical neurogenesis and neuronal migration.
1Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; BCMB Graduate Program, Weill Cornell Medical College, New York, NY, USA.
Wiley Interdisciplinary Reviews. Developmental Biology
|September 10, 2013
Summary
Neocortex development involves progenitor cell division to create neurons and precise migration for layered structure formation. This review covers molecular and cellular processes in neocortical neurogenesis and neuronal migration.
Area of Science:
- Neuroscience
- Developmental Biology
Background:
- The neocortex, crucial for complex behaviors, develops from progenitor cells.
- Neurons in the neocortex form organized layers essential for function.
- Neuronal migration is a key process in establishing neocortical laminar structure.
Purpose of the Study:
- To provide an overview of neocortical neurogenesis.
- To review the molecular and cellular mechanisms of neuronal migration in the developing neocortex.
Main Methods:
- Literature review of recent research on neocortical development.
- Synthesis of findings on progenitor cell division and neuronal migration.
Main Results:
- Advances in understanding excitatory and inhibitory interneuron production.
- Insights into the molecular control of neuronal positioning.
Conclusions:
- Neocortical development relies on tightly regulated neurogenesis and migration.
- Further research continues to elucidate these complex processes.
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