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Updated: May 8, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Published on: September 14, 2010

Bilateral auricular classic Kaposi's sarcoma.

Giacomo Colletti¹, Fabiana Allevi, Laura Moneghini

¹Department of Maxillofacial Surgery, San Paolo Hospital, University of Milan, Milan, Italy.

BMJ Case Reports

|September 10, 2013

Summary

A rare reddish-purplish ear lesion, potentially Kaposi

Area of Science:

Dermatology
Maxillofacial Surgery
Oncology

Background:

A 57-year-old male presented with a recurrent reddish-purplish swelling on the helix of his ear.
The patient had no known predisposing factors, including smoking, alcohol use, or a family history of similar lesions or Kaposi's sarcoma.

Observation:

The initial lesion, over 1 cm, persisted for 3 months before complete excision and reconstruction.
Recurrent lesions appeared on the contralateral auricle in 2011 and a smaller lesion on the left helix in 2012, both surgically removed.

Findings:

The case describes a unique presentation of a recurring, localized, reddish-purplish auricular lesion in an immunocompetent patient.
Histopathological analysis confirmed the nature of the lesion, though not explicitly stated in the abstract, it guided treatment.

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Implications:

This case highlights the importance of vigilant monitoring and complete excision for recurrent auricular lesions, even in the absence of typical risk factors.
Further research may be needed to understand the etiology of such isolated, recurrent lesions in immunocompetent individuals.