Outcomes of children after esophagogastroduodenoscopy for chronic abdominal pain

Kalpesh Thakkar1, Leon Chen1, Mary E Tessier1

  • 1Section of Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, Texas.

Insights

Esophagogastroduodenoscopy (EGD) accurately diagnosed 38% of children with chronic abdominal pain. This procedure identified treatable conditions, with 67% of patients responding well to medical therapy within a year.

Area of Science:

  • Pediatric Gastroenterology
  • Diagnostic Endoscopy

Background:

  • Chronic abdominal pain is a common reason for pediatric esophagogastroduodenoscopy (EGD).
  • Limited data exists on the diagnostic accuracy and patient outcomes following EGD for this indication.

Purpose of the Study:

  • To evaluate the diagnostic yield of EGD in children with chronic abdominal pain.
  • To assess the short-term outcomes of pediatric patients undergoing EGD for abdominal pain.

Main Methods:

  • A prospective study included 290 children (4-18 years) with chronic abdominal pain undergoing EGD.
  • Data collected included demographics, alarm features, Rome III criteria, and EGD findings.
  • Patients with diagnostic lesions were followed for at least one year for outcomes.

Main Results:

  • EGD provided an accurate diagnosis in 38% of children.
  • Common diagnoses included esophagitis (21.0%), eosinophilic gastroenteritis (4.1%), and H. pylori infection (2.0%).
  • Medical therapy was effective in approximately 67% of patients with diagnostic findings.

Conclusions:

  • EGD is a valuable diagnostic tool for pediatric chronic abdominal pain, with a 38% diagnostic yield.
  • The procedure identifies treatable gastrointestinal disorders, leading to effective medical management in a majority of cases.
Abstract

Related Concept Videos

Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

Peptic Ulcer Disease III: Clinical Manifestations and Complications

Duodenal UlcersDuodenal ulcers are the most common form of peptic ulcer disease, presenting with chronic, intermittent epigastric pain. Pain typically appears 2–3 hours after meals, especially when the stomach is empty, often waking patients at night. It is characteristically relieved by food or antacids (“pain–food–relief”). Some patients remain asymptomatic until complications like bleeding or perforation emerge, particularly with NSAID or anticoagulant use.Gastric UlcersGastric ulcers share...
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...