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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...

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Related Experiment Video

Updated: May 8, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

[Peripheral nerve disorders as common diseases].

Satoshi Kuwabara1

  • 1Department of Neurology, Graduate School of Medicine, Chiba University.

Brain and Nerve = Shinkei Kenkyu No Shinpo
|September 11, 2013
PubMed
Summary
This summary is machine-generated.

Peripheral neuropathy is a common condition affecting up to 10% of people, with diverse causes and impacts. Improved collaboration is needed for better patient care and quality of life.

Related Experiment Videos

Last Updated: May 8, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

Area of Science:

  • Neurology
  • Epidemiology
  • Pathology

Context:

  • Peripheral neuropathy encompasses a wide range of conditions, including diabetic neuropathy, alcoholic neuropathy, and carpal tunnel syndrome.
  • The incidence of chemotherapy-induced neuropathy is rising.
  • Existing epidemiological data on peripheral nerve disorders is limited, despite a high estimated prevalence.

Purpose:

  • To highlight the heterogeneity and prevalence of peripheral neuropathies.
  • To emphasize the need for comprehensive epidemiological studies.
  • To underscore the crucial role of neurologists in managing these disorders.

Summary:

  • Peripheral neuropathy presents diverse causes, pathologies, and severities, affecting a significant portion of the population.
  • Key disorders include diabetic, alcoholic, and chemotherapy-induced neuropathies, alongside carpal tunnel syndrome.
  • Neurologists play a vital role in both fundamental and symptomatic treatments, including neuropathic pain and autonomic dysfunction.

Impact:

  • Calls for enhanced collaboration between neurologists, oncologists, and general physicians.
  • Aims to improve the quality of life for patients with peripheral nerve disorders.
  • Highlights the increasing importance of managing HIV-related and drug-induced neuropathies.