[(11)Treatment of glioma. State-of-the-art: a series of 1,036 surgeries on 944 cases]

The author's own experience of 1,036 surgeries on 944 glioma cases in the period between 1993 to 2011(mostly at the University Hospital Zurich)are presented. Glioblastoma cases were the most frequent, amounting to ca. 30% of cases as is shown in Fig.4A. They were operated on 1.3 times on the average but the most frequent repetition-surgery was in cases with fibrillary astrocytomas(Fig.1), as these tended to transform into secondary glioblastomas which needed surgery again. The latter amounting to 10% of glioblastoma cases that had transformed from astrocytoma in the course of 3.8 years on the average(Fig.4B). With modern "state-of-the-art" treatment of glioma(Table), survival term for glioblastoma patients has clearly improved. This can be seen by comparison of figures between generations(Fig.4C, D):Prof. Krayenbuhl's era(macrosurgery±RT), Prof. Yasargil's era(microsurgery+RT)and the most recent part of my treatment(microsurgery+ "state-of-the-art" treatment). Representative cases of various glioma are presented in which "cured" cases of glioblastoma are also included.