Thyrotoxicosis in pregnancy:: A case report

Area of Science:

• Obstetrics and Gynecology
• Endocrinology
• Reproductive Medicine

Background:

• Hyperthyroidism complicates pregnancy with diverse etiologies, including Graves' disease and gestational thyrotoxicosis.
• Elevated human chorionic gonadotropin (hCG) from trophoblastic tissue, such as in hydatidiform moles, can stimulate the thyroid.
• Understanding hCG-mediated thyroid stimulation is crucial for managing pregnant patients.

Purpose of the Study:

• To present a case of hyperthyroidism in pregnancy secondary to a hydatidiform mole.
• To illustrate the resolution of hyperthyroidism following the evacuation of a hydatidiform mole.
• To emphasize the importance of considering molar pregnancy in the differential diagnosis of hyperthyroidism during gestation.

Main Methods:

• Case report of a pregnant patient.
• Clinical presentation of hyperthyroidism.
• Diagnosis of hydatidiform mole.
• Management by mole evacuation.
• Post-operative monitoring of thyroid function.

Main Results:

• The patient presented with symptoms of hyperthyroidism.
• A hydatidiform mole was diagnosed during pregnancy.
• Following surgical evacuation of the mole, the patient's hyperthyroid state resolved.
• Thyroid function normalized without further intervention.

Conclusions:

• Hydatidiform mole is a significant, albeit less common, cause of hyperthyroidism in pregnancy.
• Evacuation of the hydatidiform mole effectively treats the associated hyperthyroidism.
• This case underscores the importance of timely diagnosis and management of molar pregnancies for maternal well-being.