Posttraumatic glioma: report of a case
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Updated: May 8, 2026
Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
Aldo Spallone1, Chiara Izzo, Augusto Orlandi
1Section of Neurosurgery, Department of Clinical Neurosciences, Neurological Centre of Latium 'NCL', Rome, Italy ; Department of Biopathology, Institute of Anatomical Pathology, Tor Vergata University of Rome, Rome, Italy.
Abstract:
For a long time, head injury has been considered as a possible causative factor for later development of brain tumors. However, the actual role of previous head trauma in the pathogenesis of intracranial tumors is still a matter of debate, also due to the possible medico-legal implications. Some authors have suggested several criteria for establishing a possible causal relationship between the aforementioned factors. We report a case of a left posterior paraventricular high-grade glioma which developed 20 years after a posttraumatic hematoma occurring in the same area. This case is reported in detail and the relevant literature is reviewed.
