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Updated: May 8, 2026

A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
Published on: January 6, 2023
[Silicosis and industrial bronchitis by exposure to silica powders and cement]
María Martha Méndez-Vargas1, Fabiola Berenice Báez-Revueltas, Pablo López-Rojas
1Universidad Nacional Autónoma de México, Mexico City, Mexico. ramazzini.1700@gmail.com
Objective:
to identify the association between the exposure of workers to inorganic dust in a quarry and a cement factory and pulmonary diseases.
Methods:
a transverse study on data from 32 quarry workers (QWs) and 57 cement production line workers (CFWs) to inorganic-dust exposure was performed. Pulmonary function tests and chest X ray were done in both groups.
Results:
there were differences between QWs and the CFWs; QWs were younger, shorter and thinner. The number of sick individuals might be considered significantly different, showing a smaller proportion on the cement production line. The quarry workers have been on the company for a shorter period of time and, in the end, they present more serious pulmonary problems with an average of 3 years working.
Conclusions:
the amount of free-silica that is managed on the quarry affects the workers in some way, even when literature states that the evolution of industrial bronchitis and silicosis have a period development of approximately 10 years.
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