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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Blaschkoid lichen planus: Not a Koebner phenomenon.

Nitin Ramchandra Lade1, Vikrant Saoji, Adarsh Iata Singh

  • 1J N Medical College Wardha, Maharashtra, India.

Dermatology Online Journal
|September 12, 2013
PubMed
Summary

Linear lichen planus (LP) typically follows the Koebner phenomenon. This case highlights a rare whorl pattern of LP along Blaschko lines, observed in a female patient.

Area of Science:

  • Dermatology
  • Cutaneous Medicine
  • Histopathology

Background:

  • Linear lichen planus (LP) is a recognized dermatosis often associated with the Koebner phenomenon.
  • LP can manifest in various patterns and locations across the skin.
  • The Koebner phenomenon describes the isomorphic response of skin lesions.

Observation:

  • A rare presentation of LP was observed in a 32-year-old female.
  • The patient exhibited multiple hyperpigmented lesions arranged in diverse patterns.
  • Lesions were specifically located along Blaschko lines on the left side of the trunk.

Findings:

  • Clinical examination revealed lesions consistent with lichen planus.
  • Histopathological analysis supported the diagnosis of lichen planus.

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  • The unique whorl pattern along Blaschko lines is a key finding.

    • Implications:

    • This case expands the known clinical spectrum of lichen planus.
    • It underscores the importance of considering LP in unusual linear or whorled patterns.
    • Further research may elucidate the specific mechanisms driving LP along Blaschko lines.