Related Experiment Video
Updated: May 8, 2026

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol
Daniel Woo1, Jonathan Rosand, Chelsea Kidwell
1From the University of Cincinnati, College of Medicine, OH (D.W., J.O., M.F.); Massachusetts General Hospital, Harvard Medical School, Boston, MA (J.R.); Department of Neurology, Georgetown University Medical Center, Washington, DC (C.K.); John P. Hussman Institute for Human Genomics, University of Miami, FL (J.L.M., S.E.W.); Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC (M.W.B., C.D.L.); Institute for Policy Research, University of Cincinnati, OH (E.W.R.); National Institute of Neurological Disorders and Stroke, Bethesda, MD (S.W., J.N.R.); University of Miami, Miller School of Medicine, FL (S.K., R.I.S.); University of Texas Medical School-Houston, TX (N.R.G., R.M.); University of Southern California, Neurocritical Care and Stroke Division, Los Angeles, CA (G.S.); University of Maryland, Baltimore Veterans Administration Medical Center, MD (S.K.); University of Texas Health Science Center at San Antonio, TX (L.B., F.J., A.L.); Emory University, Grady Memorial Hospital, Atlanta, GA (M.F.); University of Illinois at Chicago Medical Center, IL (F.D.T.); Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX (C.E.H.); Columbia University, New York, NY (M.S.V.E.); University of Arizona, Tucson, AZ (B.C.); St. Luke's-Roosevelt Hospital Center, New York, NY (J.Y.C.); University of California San Francisco, Fresno, CA (T.W.); University of New Mexico, Albuquerque, NM (M.M.); Department of Anesthesiology, Duke University, Durham, NC (M.L.J.); University of California, Los Angeles, CA (L.K.A.); Department of Neurology and Public Health Sciences, University of Virginia, Charlottesville, VA (B.B.W.); and Department of Neurology, University of Maryland School of Medicine, Baltimore, MD (T.W.).
The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study investigates disparities in brain bleeds across diverse populations. This case-control study aims to identify genetic and environmental risk factors contributing to intracerebral hemorrhage (ICH).
Area of Science:
- Neurology
- Epidemiology
- Genetics
Background:
- Intracerebral hemorrhage (ICH) incidence, location, and outcomes vary significantly across racial and ethnic groups.
- Previous epidemiological studies highlight these disparities but lack detailed investigation into underlying causes.
Purpose of the Study:
- To design and implement a large, prospective, multi-center case-control study to investigate ethnic and racial variations in intracerebral hemorrhage (ICH).
- To identify genetic and epidemiological risk factors contributing to ICH and its outcomes in diverse populations.
Main Methods:
- The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study employs a prospective case-control design.
- Cases are identified via hot pursuit, with data collection including phenotype, risk factors, neuroimaging, and blood samples.
- Controls are matched by age, race, ethnicity, sex, and region using random digit dialing.
Main Results:
- As of March 2013, 1655 ICH cases and 851 controls were recruited, exceeding the case target.
- The enrolled cases comprised 38% non-Hispanic black, 28% non-Hispanic white, and 34% Hispanic individuals.
- Neuroimaging data, including 24-hour follow-up CT scans and MRI evaluations, were collected for a substantial portion of cases.
Conclusions:
- The ERICH study successfully recruited a large cohort with a significant representation of minority populations.
- This study provides a robust platform for identifying genetic and epidemiological risk factors for ICH.
- Findings will elucidate disparities in ICH incidence, presentation, and outcomes among different racial and ethnic groups.
More Related Videos
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology

